PED-HEME/ONC BASIC RESEARCH (IN-PHMB-IUINA)

The Herman B Wells Center for Pediatric Research conducts basic science and translational research within the Department of Pediatrics at Indiana University School of Medicine. The Wells Center houses more than 200 faculty investigators, staff, and trainees seeking answers to the most pressing questions related to childhood illness.

With the collaboration between scientists and physicians, the center aims to increase knowledge of causes and mechanisms of serious pediatric diseases. Our goal is to develop innovative approaches to the diagnosis and treatment of sick children in Indiana and beyond.

This lab studies the regulation of immunity by long noncoding RNAs. The current focus is understanding how long noncoding RNAs regulate T cells that cause acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Department-Specific Responsibilities

• Conducts in vitro and in vivo bone marrow transplantation/graft-versus-host disease/immunology experiments.
• Conducts routine molecular biology techniques, especially RNA isolation, qRT-PCR, cytotoxicity assays, cloning, gel electrophoresis, western blotting, tissue culture, and flow cytometry.
• Assists with mouse colony maintenance.
• Assists other team members in their projects when needed.
• Collects, analyzes, and processes research data, reporting to the Principal Investigator (PI) or their designee.
• Works in collaboration with Principal Investigator or their designee on other projects as needed.
• Assists with lab ordering and administrative aspects.
• Assists with bio-safety, radiation safety and regulatory compliance related to both animal and human subject research specimens.
• Participates in laboratory meetings.
• Responsible for accurate research record keeping.

General Responsibilities

• Performs complex and intricate laboratory experiments while following research techniques and procedures.
• Develops procedures and protocols in collaboration with leadership.
• Prepares research reports or analyses for projects.
• Maintains safety records and ensures safety/compliance procedures and protocols are followed.
• Provides guidance and support to junior-level staff in laboratory operations.
• May develop, prepare, and coordinate grant applications and grant-related activities to obtain funding for research projects and related work.

This position is posted at the Career Career Level but may be filled at the Core Career Level depending on the candidate's qualifications. Although they will be similar, the duties and responsibilities may differ if filled at the lower rank. Please see the qualifications for each level listed below.

Career Requirements:

EDUCATION

Required

• Bachelor's degree in related field

Preferred

• Master's degree in related field

WORK EXPERIENCE

Required

• 3 years of related work experience

Combinations of related education and experience may be considered

SKILLS

Required

• Proficient communication skills
• Maintains a high degree of professionalism
• Demonstrated time management and priority setting skills
• Demonstrates a high commitment to quality
• Possesses flexibility to work in a fast paced, dynamic environment
• Seeks to acquire knowledge in area of specialty
• Highly thorough and dependable
• Demonstrates a high level of accuracy, even under pressure

Preferred

• Working knowledge of principles of molecular biology, microbiology, and immunology
• Excellent interpersonal and organizational skills
• Ability to work independently and as a member of our team
• Excellent attendance, ability to prioritize appropriately and exercise good judgment
• Willingness to work with mouse models and human samples
• Ability to comply with University research policies and procedures
• Ability to commit at least 1 year to position
• Experience with molecular biology techniques especially the manipulation of RNA, high-throughput sequencing, and bioinformatics
• Experience with research with in vitro tissue culture systems
• Experimental work with mice and mouse tissues
• Proficiency with Microsoft Word, PowerPoint, and Excel, and proficiency or ability to learn EndNote reference manager, Graphpad data analysis software, and FlowJo flow cytometry analysis software

Core Requirements:

EDUCATION

Required

• Bachelor's degree in related field

Combinations of related education and experience may be considered

SKILLS

Required

• Proficient communication skills
• Maintains a high degree of professionalism
• Demonstrated time management and priority setting skills
• Demonstrates a high commitment to quality
• Possesses flexibility to work in a fast paced, dynamic environment
• Seeks to acquire knowledge in area of specialty

The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The role requires the ability to move objects weighing up to 25 pounds and will occasionally work near moving mechanical parts. The person in this role must be able to perform the essential functions with or without an accommodation.

The salary range for the career level position is $55,000 - $65,000. Salary determination is based on experience, skill level, education, and training.

Should the position be filled at the core career level, the salary range for this position is $45,000-$50,000. Salary determination is based on experience, skill level, education, and training.

Indianapolis, Indiana

For full-time staff employees, Indiana University offers a wide array of benefits including:

• Multiple plan options for medical insurance
• Dental insurance
• Health Savings Account with generous IU contribution
• Life insurance, LTD, and AD&D options
• Base retirement plan contribution from IU, subject to vesting
• Additional supplemental retirement plan options
• Tuition benefit for IU classes
• 10 paid holidays per year
• Generous Paid Time Off
• Paid Parental Leave
• Employee Assistance Program (EAP)

Learn more about our benefits by reviewing our online Benefits Brochure.

Career Level: Career

FLSA: Exempt

Job Function: Research

Job Family: Research Analysis

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Due to the COVID-19 pandemic, there may be differences in the working conditions as advertised in our standard job postings (e.g., the ability to travel from one campus to another, etc.). If you are invited for an interview, please discuss your questions or concerns regarding the working conditions at that time.

This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.

If you wish to include a cover letter, you may include it with your resume when uploading attachments.

New employees will be provided with information regarding Indiana University's COVID-19 vaccine policy, which includes the opportunity to request an exemption. To learn more, view our COVID-19 vaccine information page.

Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All qualified applicants will receive consideration for employment based on individual qualifications. Indiana University prohibits discrimination based on age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status or protected veteran status. Indiana University does not discriminate on the basis of sex in its educational programs and activities, including employment and admission, as required by Title IX. Questions or complaints regarding Title IX may be referred to the U.S. Department of Education Office for Civil Rights or the university Title IX Coordinator. See Indiana University's Notice of Non-Discrimination here which includes contact information.

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